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Next Interactions and BASF Agricultural Solutions Develop New Technology to Analyze Asian Soybean Rust


Posted: October 14, 2021 at 6:00 a.m. MDT|Update: 9 minutes ago

RICHMOND, Calif., October 14, 2021 / PRNewswire / – Next Interactions and BASF’s Agriculture Solutions division are collaborating to develop a unique scientific approach to tackle Asian soybean rust (ASR), one of the most harmful fungal diseases in soybeans. With around 300 to 400 million tonnes produced per year, soybeans are one of the most important crops for human consumption and animal feed. In particular in South America, ASR can destroy up to 90% of the crop. To offer producers more flexibility and more sustainable solutions to fight against the fungus in the future, BASF Agricultural Solutions is developing, using Next Interactions technology, new soybean varieties with increased resistance to this fungus. .

As part of its disease resistance research, BASF Agricultural Solutions is working to understand the interaction of ASR fungus with soybeans and has partnered with Next Interactions to analyze the function of potential ASR effector proteins, that allow the disease to spread.

Plant pathogens such as ASR secrete a variety of effector proteins in plant host cells. Once inside, these effectors interfere with the host cell’s metabolism and block defense pathways, allowing disease to spread. Recent sequencing of the fungus genome has revealed the existence of an extraordinarily large number of ASR effectors.

Next Interactions uses its protein interaction mapping and screening platform technology that combines two yeast hybrids with next-generation sequencing (NGS-Y2H) to thoroughly analyze the interaction of ASR effectors with soy proteins.

“Next Interactions’ scientific approach and trusting cooperation have been very valuable in strengthening our knowledge about ASR disease. It provides an overview of ways to develop new products to combat this pathogen, offers soybean producers more flexibility in the field and promotes more sustainable agriculture, helping farmers to balance agricultural productivity, protecting the environment. environment and the needs of society. BASF is committed to providing producers with solutions to help control RPA, and our collaboration with Next Interactions reflects this commitment, ”said Linda trolinder, Senior Vice President Research & Development Seeds & Traits at BASF Agricultural Solutions.

Bernhard Suter, CEO of Next Interactions, added: “The combination of BASF Agricultural Solutions ‘expertise in disease resistance research and Next Interactions’ know-how in scientific technology enables a successful transfer of science to agricultural products of the future, while supporting more sustainable agriculture. “

About the following interactions

Next Interactions offers a suite of services including custom screens, protein engineering and functional assays for clients in pharmaceutical, biotechnology and academic research. NGS readings and completely redesigned components for Y2H provide complete and accurate measurements of protein binding and protein assemblies. The Next Generation Interaction Sequencing (NGIS) platform can be applied to research in the fields of human health, energy, food safety and sustainability. For more information, visit https://nextinteractions.com.

CONTACT: Bernhard Suter, [email protected]

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